Des documents enfouis dans un fauteuil pendant soixante-dix ans peuvent transformer un historien en détective, surtout s'ils sont estampillés de la croix gammée. Le nazisme est un sujet que Daniel Lee maîtrise, pourtant le nom du propriétaire de ces papiers lui est inconnu. Lorsqu'il décide de retracer son itinéraire, il découvre qu'il s'agit d'un officier SS qui, dans les années 1930, a exercé comme juriste à l'hôtel Silber, quartier général de la Gestapo à Stuttgart. Peu à peu se dessine le parcours de cet homme, qui a sillonné la France, puis l'Ukraine au sein de la Wehrmacht. Son rôle et sa responsabilité dans la machine criminelle du Troisième Reich se précisent au fil de cette étonnante chronique du quotidien d'un «nazi ordinaire», dont ses deux filles ignoraient tout. Une quête acharnée de la vérité qui est aussi un puissant révélateur des non-dits et des silences familiaux du narrateur
- 27 Mai 2014
Clinical Problems in Oncology: A Practical Guide to Management is an easy-to-use, compact
reference with essential, practical information on managing oncological emergencies, as well as
the side effects and complications of cancer and its treatment. Because patient responses can vary
widely, depending on the type of treatment prescribed, this resource offers medical professionals
the specific information they need to improve the evaluation and treatment of cancer patients at
the point of care. The compact format includes a wide range of clinical information, from the dose of drugs that would
typically be used, through guidance on the practical procedures that are frequently used
to treat oncology patients. Some of the book's highlights include: o Toxicity grading and management, including at-a-glance summaries of the most common toxicities associated with chemotherapy
o Prescribing guidelines, including how to write up electrolyte replacement properly
o Information on specialised oncology procedures (such as SIR spheres), and how to manage complications
o Types of vascular access lines and how to check their position, access them and troubleshoot problems
With an expert team of writers who have contributed materials in their areas of expertise, Clinical
Problems in Oncology is an ideal reference for oncologists in training, oncologists in non-training
positions, oncology registrars and general practitioners.
This thoughtful and engaging text challenges the widely held notion of science as somehow outside of society, and the idea that technology proceeds automatically down a singular and inevitable path. Through specific case studies involving contemporary debates, this book shows that science and technology are fundamentally part of society and are shaped by it.
Draws on concepts from political sociology, organizational analysis, and contemporary social theory.
Avoids dense theoretical debate.
Includes case studies and concluding chapter summaries for students and scholars.
- 2 Octobre 2015
This book reviews the theories regarding commonly occurring developmental issues among Chinese adolescents in Hong Kong, the application of Positive Youth Development (PYD) to a large-scale primary prevention program and the impact of PYD on student well-being, indexed according to adolescent developmental issue. Using multiple strategies, it presents the overall constructs and frameworks supporting P.A.T.H.S. in response to the various psychosocial needs of Hong Kong's youth. Some of the issues covered include substance abuse, sexual behavior, internet addiction, bullying and cyber-bullying. The book argues for the effectiveness of the school-based program in promoting student well-being in modern Hong Kong society and will be of interest to undergraduate and postgraduate students, university instructors, researchers, social workers, pediatricians, youth workers, educators, administrators, psychologists, school principals and allied professionals looking to promote whole-person development in junior form students and especially those with an interest in education in China.
- 8 Février 2012
A practical and science-based approach for addressing toxicological concerns related to leachables and extractables associated with inhalation drug products Packaging and device components of Orally Inhaled and Nasal Drug Products (OINDP)?such as metered dose inhalers, dry powder inhalers, and nasal sprays?pose potential safety risks from leachables and extractables, chemicals that can be released or migrate from these components into the drug product. Addressing the concepts, background, historical use, and development of safety thresholds and their utility for qualifying leachables and extractables in OINDP, the Leachables and Extractables Handbook takes a practical approach to familiarize readers with the recent recommendations for safety and risk assessment established through a joint effort of scientists from the FDA, academia, and industry. Coverage includes best practices for the chemical evaluation and management of leachables and extractables throughout the pharmaceutical product life cycle, as well as: Guidance for pharmaceutical professionals to qualify and risk-assess container closure system leachables and extractables in drug products Principles for defining toxicological safety thresholds that are applicable to OINDP and potentially applicable to other drug products Regulatory perspectives, along with an appendix of key terms and definitions, case studies, and sample protocols Analytical chemists, packaging and device engineers, formulation development scientists, component suppliers, regulatory affairs specialists, and toxicologists will all benefit from the wealth of information offered in this important text.
Crustacean Farming: Ranching and Culture, Second edition. John F. Wickins and Daniel O'C Lee. The second edition of an extremely well-received book, Crustacean Farming, deals with all cultivated crustaceans of commercial significance, shrimp, prawns, crayfish, lobsters, crabs, and spiny lobsters, and examines the criteria by which both the feasibility and desirability of farming proposals are assessed. The characteristics and production methods of farmed and candidate crustacean species are described in sufficient detail to enable areas of profitable involvement to be distinguished form other opportunities presenting only very high risks and possibilities for serious loss. Coverage extends right from broodstock acquisition and management through to the operation of hatcheries, nurseries and on-growing units to key aspects of processing and marketing. New to this second edition are ranching and re-stocking operations together with the culture of ornamental shrimp and small crustaceans used as live food in fish and shellfish hatcheries. The sections on crustacean diseases, genetics and nutrition have been extended in the light of recent research advances. Examples of investment and operating costs of the different culture options are compared and an analysis of current trends in world crustacean markets is presented to assist in economic and financial appraisal. Special consideration is given to the place of crustacean farming within the economics of developing nations in relation to social and environmental impact in order to promote awareness of the wider implications of global developments. The consequences of recent research and technical developments are considered, together with concerns over genetic and animal welfare issues. Specific areas where further advances in technology are needed to improve the reliability or productivity of farming systems are highlighted. This important book is a vital tool and reference work for all those involved with crustacean farming worldwide.
- 26 Septembre 2005
The majority of studies on the quality of life have been conducted in Western contexts and are based on Western participants. Comparatively speaking, there are only a few studies that have been conducted in different Chinese contexts. Also, there are fewer QOL studies based on children and adolescents, or studies that examine the relationship between QOL and economic disadvantage. In addition, more research is needed to address the methodological issues related to the assessment of quality of life.
This volume is a constructive response to the challenges described above. It is the first book to cover research in Chinese, Western and global contexts in a single volume. It is a ground-breaking volume in which Chinese studies on the quality of life are collected. The book includes papers addressing family QOL, quality of life in adolescents experiencing economic disadvantage, and methodological issues in the assessment of QOL. It is written by researchers working in a variety of disciplines.
- Humana press
- 4 Juin 2008
Chronic deep brain stimulation (DBS) has been a rapidly evolving area of neurotherapeutics since its initial introduction for the treatment of Parkinson's disease and essential tremor in the 1990s. For these conditions, DBS is now considered accepted therapy for patients failing to adequately respond to m- ical treatment. Since the 1990s, new clinical indications, anatomic targets, and technologies have contributed to an expanding role for DBS in the treatment of other movement disorders such as dystonia and Tourette syndrome as well as for other neurologic disorders such as epilepsy and cluster headache. Early experience has also been reported for psychiatric syndromes, such as obs- sive-compulsive disorder and depression. Experience with DBS in psychiatric disorders is very limited but is reviewed in this volume as neuropsychiatric indications are expected to grow in coming years. Because of the rapidly increasing application of DBS for neurologic and psychiatric indications and the recruitment of increasing numbers of neu- logic, neurosurgical, and psychiatric clinicians to the field, it is appropriate to provide a resource that updates the underlying scientific background, describes methodologies and standards of treatment, and provides information on new technologies essential for clinical success and to advance the field. Deep Brain Stimulation in Neurological and Psychiatric Disorders begins with reviews of the functional anatomy and physiology of motor and nonmotor aspects of the basal ganglia and their connections, which underlie the application of DBS to neurological and psychiatric disorders.
- 12 Mars 2019
Drawing on 15 years of experience in the development and use of wearable sensors in sports science, this book bridges the gap between technical research and the widespread adoption of inertial sensors in biomechanical assessment and ambulatory studies of locomotion. It offers a 'no-nonsense' guide to using inertial sensors for readers from the sports science disciplines who may be unfamiliar with the terms, concepts and approaches that lead to these sensors' successful use. At the same time, the book introduces readers with a technical background, e.g. in engineering, to sport science methodologies that can provide valuable insights into the use of sensors in a practical environment that extends well beyond bench testing.
- 5 Novembre 2021
This book provides a complete and thorough guide to the performance of robotic urinary tract reconstruction procedures, including the principals of successful reconstructive techniques in the kidney, ureter, bladder, prostate and urethra. Reviewing patient positioning, trocar placement, instrumentation, detailed steps of procedure, and available outcome data, it outlines both common and advanced techniques, such as revision of uretero-intestinal anastomoses, buccal mucosa graft for long segment ureteral strictures, management of complex fistulas and urethral stricture. Illuminating unusual anatomy, including horseshoe kidney, retrocaval ureter, ureteral duplication, ectopic/malrotated kidneys, and retroperitoneal fibrosis, this book also highlights potential complications, their avoidance and management. Written by experts in the field, Techniques of Robotic Urinary Tract Reconstruction: A Complete Approach guides clinical practitioners in the utilization of advanced novel technology to aid intraoperation and demonstrates the ways in which robotics enables the performance of reconstructive procedures in an area difficult to reach via open techniques.
Cutaneous adverse drug reactions are common and range from the benign to those which are life-threatening. The clinical presentation of these dermatoses is varied and many may mimic common skin conditions. Consequently, diagnosis in drug-induced skin disease is challenging and the treatment considerations are complex. This book aims to bridge the divide between dermatology and allergy by providing a comprehensive review on the pathomechanisms and clinical features of cutaneous adverse drug reactions. Broken up into three distinct sections: General Considerations, Reaction Patterns, and Special Drug Categories, these chapters cover the common and rare adverse skin reactions and provide information on recent advances - particularly immunopathology and pharmacogenetics - as well as highlighting new adverse drug signals and novel therapies. Drug Eruptions is a must-have resource for dermatologists, allergists, internal physicians and general practitioners.
- Black Rose
- 1 Mai 2018
La mémoire à vif, B.J. DanielsDans la chambre d'hôpital où elle vient de se réveiller, Abby tente de se rappeler les circonstances dans lesquelles elle a perdu la mémoire. Puis, sentant près d'elle une présence, elle tourne les yeux et tressaille. Car, près de son lit, Ledger McGraw la couve du regard et annonce qu'il va la ramener chez lui pour veiller sur elle... Surprise, troublée, Abby ne comprend pas ce qui lui arrive. De qui Ledger prétend-il la protéger ? Et pour quelle raison est-ce lui, son premier amour, qui se trouve à ses côtés aujourd'hui ? Lui qui l'a abandonnée autrefois, la poussant par dépit à épouser un homme qu'elle n'aimait pas... Le passé en question, Rachel LeeAinsi ses soupçons étaient fondés ! Tout en lisant le dossier de Dory Lake, Cadell est frappé par les révélations terribles qu'il contient : le frère de Dory, qui vient de purger une peine de vingt-cinq ans pour avoir tué leur père, est sur le point d'être libéré... Cadell comprend mieux à présent les raisons de la réserve de la jeune femme et cette peur qu'il a décelée dans son regard le jour où, sans lui révéler les motifs de son angoisse, elle a fait appel à lui pour la protéger. Mais qu'importent les réticences de Dory à lui accorder sa confiance, Cadell connaît maintenant son secret et il fera tout pour qu'un sourire vienne à nouveau éclairer ce beau visage qui l'émeut tant...
- Black Rose
- 1 Avril 2010
L'étau du danger, Adrianne LeeFuir sans jamais se retourner. Et ne jamais révéler sa véritable identité. C'est le seul moyen pour Laura Whittaker de survivre depuis que l'assassin de son oncle la traque sans relâche afin de la tuer à son tour. Mais bientôt à bout de forces et tenaillée par la peur, elle se résout à demander de l'aide à celui qu'elle s'était pourtant juré de ne jamais solliciter : Jake Wilder. L'homme qu'elle a abandonné au pied de l'autel le jour même de leur mariage et qui, elle le sait, ne le lui a jamais pardonné...Sous ta protection, B.J. DanielsLiz, son amie de lycée, a été assassinée... En apprenant cette affreuse nouvelle, Karen Sutton s'effondre... puis se souvient : la veille au soir, elle en est certaine, elle a vu un homme entrer chez Liz, et avoir une violente altercation avec celle-ci. Et tandis qu'elle témoigne auprès de Jack Adams, le policier en charge de l'affaire, elle comprend qu'elle va désormais devoir vivre sous sa surveillance vingt-quatre heures sur vingt-quatre. Car si elle a vu l'assassin de Liz, alors ce dernier l'a certainement vue lui aussi, et va désormais chercher à l'éliminer...